Rabbit Monoclonal to DOCK2
货号:
P18789
别名:
DOCK 2; IMD40;;Dedicator of cytokinesis protein 2
应用:
WB;IHC
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
Q92608
规格:
目录价
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Description |
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Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2. |
Specification |
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Aliases | DOCK 2; IMD40;;Dedicator of cytokinesis protein 2 |
Swissprot | Q92608 |
WB Predicted band size | 212 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | A synthesized peptide derived from human Dedicator of cytokinesis protein 2 |
Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
Application |
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WB | 1/1000-1/2000 |
IHC | 1/100-1/200 |