Mouse Monoclonal Antibody to HDAC2
货号:
30829
别名:
HD2; RPD3; YAF1
应用:
WB,IHC,FCM
反应种属:
Human,Mouse,Monkey,Rat
抗体类型:
Primary antibody
Swissprot:
Q92769
规格:
目录价
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Description |
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This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants. |
References |
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1.Zhonghua Bing Li Xue Za Zhi. 2012 Jul;41(7):466-9. 2.J Cell Biochem. 2012 Jun;113(6):2167-77. |
Specification |
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Aliases | HD2; RPD3; YAF1 |
Entrez GeneID | 3066 |
Swissprot | Q92769 |
clone | 4D8C3 |
WB Predicted band size | 55.4kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Monkey,Rat |
Immunogen | Purified recombinant fragment of human HDAC2 (AA: 217-327) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
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WB | 1/500 - 1/2000 |
IHC | 1/200 - 1/1000 |
FCM | 1/200 - 1/400 |
ELISA | 1/10000 |
Product Image
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Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
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Western blot analysis using HDAC2 mouse mAb against Hela (1), Jurat (2), HepG2 (3), Hek293 (4), K562 (5), MCF-7 (6), NIH3T3 (7), COS7 (8) and PC-12 (9) cell lysate.
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Flow cytometric analysis of Hela cells using HDAC2 mouse mAb (green) and negative control (red).
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Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using HDAC2 mouse mAb with DAB staining.