Rabbit Monoclonal to RANBP3
货号:
P18856
别名:
Ran binding protein 3; RanBP3;;RanBP3
应用:
WB,IHC/IHF,IF,IP,FCM
反应种属:
Human,Mouse
抗体类型:
Primary antibody
Swissprot:
Q9H6Z4
规格:
目录价
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Description |
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Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein. Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction. In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex. Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1. Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner. |
Specification |
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Aliases | Ran binding protein 3; RanBP3;;RanBP3 |
Swissprot | Q9H6Z4 |
WB Predicted band size | Calculated MW: 60 kDa ; Observed MW: 70,90 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse |
Immunogen | A synthesized peptide derived from human RanBP3 |
Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
Application |
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WB | 1/1000-1/2000 |
IP | 1/20-1/50 |
IHC | IHC:1/100-1/200;IHF:1/50-1/200 |
IF | 1/50-1/200 |
FCM | 1/20-1/100 |