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Rabbit Monoclonal to Caspase-1
货号: P18881
别名: CASP-1; ICE; IL-1 beta converting enzyme; IL-1BC; IL1BCE; caspase-1;;Caspase 1
应用: WB;IP
反应种属: Human,Mouse,Rat
抗体类型: Primary antibody
Swissprot: P29466
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Description

Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.

Specification

Aliases CASP-1; ICE; IL-1 beta converting enzyme; IL-1BC; IL1BCE; caspase-1;;Caspase 1
Swissprot P29466
WB Predicted band size Calculated MW: 45 kDa ; Observed MW: 45,42,35,12,10 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen A synthesized peptide derived from human Caspase 1
Formulation Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Application

WB 1/1000-1/2000
IP 1/20-1/50
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