Mouse Monoclonal Antibody to LRP1
货号：
30851
别名：
APR; LRP; A2MR; CD91; APOER; LRP1A; TGFBR5; IGFBP3R
应用：
IHC,IF,FCM
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q07954
规格：
目录价
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Description |
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The protein encoded by this gene is an endocytic receptor involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the A2M-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer patients. |
References |
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| 1.J Biol Chem. 2014 Feb 14;289(7):4135-44. 2.Aging (Albany NY). 2013 Nov;5(11):835-49. |
Specification |
|
|---|---|
| Aliases | APR; LRP; A2MR; CD91; APOER; LRP1A; TGFBR5; IGFBP3R |
| Entrez GeneID | 4035 |
| Swissprot | Q07954 |
| clone | 3F12E2 |
| WB Predicted band size | 50.5kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human LRP1 (AA: 20-155) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
|
|---|---|
| IHC | 1/200 - 1/1000 |
| IF | 1/200 - 1/1000 |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
Product Image
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Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
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Flow cytometric analysis of Jurkat cells using LRP1 mouse mAb (green) and negative control (red).
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Immunohistochemical analysis of paraffin-embedded human esophageal cancer tissues using LRP1 mouse mAb with DAB staining.
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Immunohistochemical analysis of paraffin-embedded human stomach cancer tissues using LRP1 mouse mAb with DAB staining.
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