Mouse Monoclonal Antibody to SIRT4
货号：
30850
别名：
SIR2L4
应用：
IF,FCM
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q9Y6E7
规格：
目录价
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Description |
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This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. |
References |
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| 1.Eur J Histochem. 2011 Mar 21;55(1):e10. 2.J Biol Chem. 2014 Feb 14;289(7):4135-44. |
Specification |
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|---|---|
| Aliases | SIR2L4 |
| Entrez GeneID | 23409 |
| Swissprot | Q9Y6E7 |
| clone | 6G6D2 |
| WB Predicted band size | 35.2kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human SIRT4 (AA: 215-314) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
|
|---|---|
| IF | 1/100 - 1/500 |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
Product Image
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Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
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Immunofluorescence analysis of HeLa cells using SIRT4 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
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Flow cytometric analysis of HeLa cells using SIRT4 mouse mAb (green) and negative control (red).
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