Rabbit Monoclonal to CCDC98
货号：
P18986
别名：
ABRA1; ABRAXAS; FAM175A;;ABRAXAS1
应用：
WB,IF,IP,FCM
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q6UWZ7
规格：
目录价
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Description |
|---|
Involved in DNA damage response and double-strand break (DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs. |
Specification |
|
|---|---|
| Aliases | ABRA1; ABRAXAS; FAM175A;;ABRAXAS1 |
| Swissprot | Q6UWZ7 |
| WB Predicted band size | Calculated MW: 47 kDa ; Observed MW: 50 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | A synthesized peptide derived from human ABRAXAS1 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/1000-1/2000 |
| IP | 1/20-1/50 |
| IF | 1/50-1/200 |
| FCM | 1/20-1/100 |
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