Mouse Monoclonal Antibody to COL1A1
货号:
P20055
别名:
OI1; OI2; OI3; OI4; EDSC; CAFYD; EDSARTH1; COL1A1; Collagen I
应用:
IHC
反应种属:
Human,Mouse,Rat
抗体类型:
Primary antibody
Swissprot:
规格:
目录价
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Description |
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This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. |
Specification |
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Aliases | OI1; OI2; OI3; OI4; EDSC; CAFYD; EDSARTH1; COL1A1; Collagen I |
Entrez GeneID | 1277 |
clone | 4C4 |
WB Predicted band size | 139 kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat |
Formulation | Purified antibody in PBS with 0.03% Proclin 300,0.5%BSA and 50% glycerol. |
Application |
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IHC | 1/100-1/200 |
Product Image
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Immunohistochemistry analysis of paraffin-embedded Human Colon Carcinoma Tissue using COL1A1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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Immunohistochemical analysis of paraffin-embedded Human tonsils using Collagen COL1A1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.