Rabbit Polyclonal Antibody to Cleaved-Caspase 6 p18
货号：
P20029
别名：
CASP6; MCH2; Caspase-6; CASP-6; Apoptotic protease Mch-2
应用：
WB,IHC
反应种属：
Human,Rat
抗体类型：
Primary antibody
Swissprot：
P55212
规格：
目录价
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Description |
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Caspase-6 (Mch2) is one of the major executioner caspases functioning in cellular apoptotic processes. Upon apoptotic stimulation, initiator caspases such as caspase-9 are cleaved and activated. The activated upstream caspases further process downstream executioner caspases, such as caspase-3 and caspase-6, by cleaving them into large and small subunits, thereby initiating a caspase cascade leading to apoptosis. One of the major targets for caspase-6 is the membrane associated protein lamin A. |
Specification |
|
|---|---|
| Aliases | CASP6; MCH2; Caspase-6; CASP-6; Apoptotic protease Mch-2 |
| Entrez GeneID | 839 |
| Swissprot | P55212 |
| WB Predicted band size | Calculated MW: 33 kDa; Observed MW: 20,35 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Rat |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Caspase 6. AA range:130-179 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
| ELISA | 1/10000 |
Product Image
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Western blot analysis of Cleaved-Caspase 6 p18 in various lysates using Cleaved-Caspase 6 p18 antibody.
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Western blot analysis of Cleaved-Caspase 6 p18 in 293 lysates using Cleaved-Caspase6 p18 (D179) antibody.
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Western blot analysis of Cleaved-Caspase 6 p18 in 293 lysates treated with Etoposide using Cleaved-Caspase 6 p18 antibody.The lane on the right is blocked with the synthesized peptide.
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Immunohistochemistry analysis of paraffin-embedded Human lung carcinoma tissue using Caspase 6 (Cleaved-Asp16, 2) antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Sample with blocking peptide on the right.
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