Mouse Monoclonal Antibody to RAD18
货号：
30860
别名：
RNF73
应用：
FCM
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q9NS91
规格：
目录价
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Description |
|---|
The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens. |
References |
|---|
| 1.Nucleic Acids Res. 2013 Feb 1;41(4):2296-312. 2.J Exp Clin Cancer Res. 2009 Jul 25;28:106. |
Specification |
|
|---|---|
| Aliases | RNF73 |
| Entrez GeneID | 56852 |
| Swissprot | Q9NS91 |
| clone | 2G8D12 |
| WB Predicted band size | 56.2kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human RAD18 (AA: 332-430) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
|
|---|---|
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
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