Rabbit Monoclonal Antibody to Phospho-mTOR (Ser2448)
货号：
P20131
别名：
MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1; Serine/threonine-protein kinase mTOR; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; Mammalian target of rapamycin; mTOR; Mechanistic tar
应用：
WB,IHC
反应种属：
Human,Mouse
抗体类型：
Primary antibody
Swissprot：
P42345
规格：
目录价
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Description |
|---|
An atypical kinase belonging to the PIKK family of kinases. Controls cell growth through protein synthesis regulation. Downstream of PI3K/Akt pathway and required for cell survival. Acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. |
Specification |
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|---|---|
| Aliases | MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1; Serine/threonine-protein kinase mTOR; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; Mammalian target of rapamycin; mTOR; Mechanistic tar |
| Entrez GeneID | 2475 |
| Swissprot | P42345 |
| WB Predicted band size | Calculated MW: 289 kDa; Observed MW: 289 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Ser2448 of human mTOR |
| Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
Product Image
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Western blot analysis of Phospho-mTOR (Ser2448) in Hela, Hela+EGF lysates using Phospho-mTOR (Ser2448) antibody.
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Western blot analysis of mTOR (Phospho-Ser2448) in 3t3 lysates using mTOR (Phospho-Ser2448) antibody.
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Immunohistochemistry analysis of paraffin-embedded Human lung cancer using Phospho-mTOR (Ser2448) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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