产品中心
PRODUCT CENTER
首页 »产品中心 »抗体 »科研抗体 »
Mouse Monoclonal Antibody to PPARA
货号: 30858
别名: PPAR; NR1C1; hPPAR; PPARalpha
应用: WB,FCM
反应种属: Human,Monkey
抗体类型: Primary antibody
Swissprot: Q07869
规格:
目录价
在线咨询

Description

Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined.

References

1.Blood. 2013 Aug 8;122(6):969-80.
2.Leukemia. 2013 Apr;27(5):1090-9.

Specification

Aliases PPAR; NR1C1; hPPAR; PPARalpha
Entrez GeneID 5465
Swissprot Q07869
clone 5D10C3
WB Predicted band size 52.2kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Monkey
Immunogen Purified recombinant fragment of human PPARA (AA: 1-120) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

WB 1/500 - 1/2000
FCM 1/200 - 1/400
ELISA 1/10000
联系我们
  • 电话:17771420241 18911818852
  • 联系人:刘经理
  • 地址:湖北省武汉市东湖新技术开发区高新大道666号光谷生物城C6栋C6403、C6404
微信公众号
版权所有 © 武汉博开生物科技有限公司  备案编号:鄂ICP备2024052832号-1鄂公网安备42018502007531号
17771420241 18911818852