Rabbit Monoclonal Antibody to Phospho-ERK1/2 (Thr202/Tyr204)/(Thr185/Tyr187)
货号：
P20220
别名：
MAPK1/MAPK3
应用：
WB,IP
反应种属：
Human,Rat
抗体类型：
Primary antibody
Swissprot：
P27361/P28482
规格：
目录价
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Description |
|---|
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements. |
Specification |
|
|---|---|
| Aliases | MAPK1/MAPK3 |
| Entrez GeneID | 5595/5594 |
| Swissprot | P27361/P28482 |
| WB Predicted band size | Calculated MW: 44,42 kDa; Observed MW: 44,42 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Rat |
| Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Thr202/Tyr204 of human Erk1 |
| Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IP | 1/10-1/20 |
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