Rabbit Polyclonal Antibody to Phospho-MSK1 (Ser376)
货号：
P20245
别名：
RPS6KA5; MSK1; Ribosomal protein S6 kinase alpha-5; S6K-alpha-5; 90 kDa ribosomal protein S6 kinase 5; Nuclear mitogen- and stress-activated protein kinase 1; RSK-like protein kinase; RSKL
应用：
WB,IP,IHC,IF
反应种属：
Human,Rat
抗体类型：
Primary antibody
Swissprot：
O75582
规格：
目录价
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Description |
|---|
Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes. Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin. |
Specification |
|
|---|---|
| Aliases | RPS6KA5; MSK1; Ribosomal protein S6 kinase alpha-5; S6K-alpha-5; 90 kDa ribosomal protein S6 kinase 5; Nuclear mitogen- and stress-activated protein kinase 1; RSK-like protein kinase; RSKL |
| Entrez GeneID | 9252 |
| Swissprot | O75582 |
| WB Predicted band size | Calculated MW: 90 kDa; Observed MW: 90 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Rat |
| Immunogen | A synthesized peptide derived from human Phospho-MSK1 (S376) |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IP | 1/10-1/20 |
| IHC | 1/50-1/100 |
| IF | 1/50-1/200 |
Product Image
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Western blot analysis of Phospho-MSK1 (S376) in HEK293 lysates treated with EGF using Phospho-MSK1 (Ser376) antibody.
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Immunohistochemistry analysis of paraffin-embedded Human lung cancer using Phospho-MSK1 (S376) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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