Rabbit Polyclonal Antibody to Phospho-IRS1 (Ser636)
货号：
P20264
别名：
IRS1; Insulin receptor substrate 1; IRS-1
应用：
WB,IHC,IF
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P35568
规格：
目录价
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Description |
|---|
May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit . |
Specification |
|
|---|---|
| Aliases | IRS1; Insulin receptor substrate 1; IRS-1 |
| Entrez GeneID | 3667 |
| Swissprot | P35568 |
| WB Predicted band size | Calculated MW: 132 kDa; Observed MW: 150 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | The antiserum was produced against synthesized peptide derived from human IRS-1 around the phosphorylation site of Ser636. AA range:603-652 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
| IF | 1/50-1/200 |
| ELISA | 1/10000 |
Product Image
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Western blot analysis of Phospho-IRS1 (Ser636) in SH-SY5Y lysates using Phospho-IRS1 (S636) antibody.
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Immunohistochemistry analysis of paraffin-embedded Human brain using Phospho-IRS1 (Ser636) antibody.High-pressure and temperature Tris-EDTA pH 8.0 was used for antigen retrieval. Sample with blocking peptide on the right.
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