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Mouse Monoclonal Antibody to NTRK2
货号: 30883
别名: TRKB; trk-B; GP145-TrkB
应用: IHC
反应种属: Human
抗体类型: Primary antibody
Swissprot: Q16620
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Description

This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.

References

1.Br J Cancer. 2014 Jun 10;110(12):2923-34.
2.Cancer Med. 2014 Feb;3(1):25-35.

Specification

Aliases TRKB; trk-B; GP145-TrkB
Entrez GeneID 4915
Swissprot Q16620
clone 10B6C4
WB Predicted band size 92kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human NTRK2 (AA: 207-339) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

IHC 1/200 - 1/1000
ELISA 1/10000
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