Rabbit Polyclonal Antibody to Phospho-HDAC6 (Ser22)
货号：
P20330
别名：
HDAC6; KIAA0901; JM21; Histone deacetylase 6; HD6
应用：
WB
反应种属：
Human,Mouse
抗体类型：
Primary antibody
Swissprot：
Q9UBN7
规格：
目录价
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Description |
|---|
Involved in the regulation of many cellular processes, including cell migration, immune synapse formation, viral infection, and degradation of misfolded proteins. HDAC6 binds to both poly-ubiquitinated misfolded proteins and dynein motors, facilitating the transport of misfolded proteins to the aggresome. Required for subsequent recruitment of the autophagic machinery and clearance of aggresomes from the cell. Plays a key role in the protection against the deleterious effects of pathological protein aggregation that occurs in various diseases. |
Specification |
|
|---|---|
| Aliases | HDAC6; KIAA0901; JM21; Histone deacetylase 6; HD6 |
| Entrez GeneID | 10013 |
| Swissprot | Q9UBN7 |
| WB Predicted band size | Calculated MW: 131 kDa; Observed MW: 131 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Synthetic peptide of human HDAC6 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
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