Rabbit Polyclonal Antibody to Phospho-Cardiac Troponin I (Ser22/Ser23)
货号：
P20290
别名：
TNNI3; TNNC1; Troponin I; cardiac muscle; Cardiac troponin I
应用：
WB,IHC
反应种属：
Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P23693
规格：
目录价
在线咨询
Description |
|---|
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: tnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). |
Specification |
|
|---|---|
| Aliases | TNNI3; TNNC1; Troponin I; cardiac muscle; Cardiac troponin I |
| Entrez GeneID | 29248 |
| Swissprot | P23693 |
| WB Predicted band size | Calculated MW: 24 kDa; Observed MW: 28 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Mouse,Rat |
| Immunogen | The antiserum was produced against synthesized peptide derived from rat TNNI3 around the phosphorylation site of Ser22 and Ser23. AA range:5-54 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
| ELISA | 1/10000 |
Product Image
-
EnzymeLinked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phospho-peptide (Phospho-left) and NonPhospho-peptide (Phospho-right), using TNNI3 (Phospho-Ser22+Ser23) antibody.
-
Western blot analysis of Phospho-Cardiac Troponin I (Ser22/Ser23) in SH-SY5Y lysates using Phospho-Cardiac Troponin I (Ser22/Ser23) antibody.
-
Western blot analysis of Phospho-Cardiac Troponin I (Ser22/Ser23) in mouse heart lysates using Phospho-Cardiac Troponin I (Ser22/Ser23) antibody.The lane on the right is blocked with the Phospho- peptide.
-
Immunohistochemistry analysis of paraffin-embedded Human skeletal muscle using TNNI3 (Phospho-Ser22+Ser23) antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.Sample with blocking peptide on the right.
鄂公网安备42018502007531号
