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Mouse Monoclonal Antibody to RAD52
货号: 30897
别名:
应用: WB,IF,FCM
反应种属: Human
抗体类型: Primary antibody
Swissprot: P43351
规格:
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Description

The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA recombination and repair. A pseudogene of this gene is present on chromosome 2. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

References

1.Blood. 2013 Aug 15;122(7):1293-304.
2.PLoS One. 2012;7(11):e50461.

Specification

Entrez GeneID 5893
Swissprot P43351
clone 5E11E7
WB Predicted band size 46.2kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human RAD52 (AA: 269-418) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

WB 1/500 - 1/2000
IF 1/200 - 1/1000
FCM 1/200 - 1/400
ELISA 1/10000
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