Rabbit Polyclonal Antibody to Phospho-GSK3 (Tyr279/Tyr216)
货号：
P20345
别名：
Serine/threonine-protein kinase GSK3A
应用：
WB,IHC,IF
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P49840
规格：
目录价
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Description |
|---|
GSK3A a proline-directed protein kinase of the GSK family. Implicated in the control of several regulatory proteins including glycogen synthase, Myb, and c-Jun. GSK3 and GSK3 have similar functions. GSK3 phophorylates tau, the principal component of neurofibrillary tangles in Alzheimer disease and is required for maximal production of amyloid plaque peptides by secretase. |
Specification |
|
|---|---|
| Aliases | Serine/threonine-protein kinase GSK3A |
| Entrez GeneID | 2931 |
| Swissprot | P49840 |
| WB Predicted band size | Calculated MW: 51 kDa; Observed MW: 46,51 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human GSK3A |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
| IF | 1/100-1/200 |
Product Image
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Western blot analysis of Phospho-GSK3 (Tyr279/Tyr216) in 293 lysates using Phospho-GSK3 alpha/beta (Tyr279/Tyr216) antibody.
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Immunofluorescence analysis of Phospho-GSK3 (Tyr279/Tyr216) in Hela cells using GSK3a/b(Phospho-Tyr279/216) antibody(red).
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Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue using Phospho-GSK3 (Tyr279/Tyr216) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Sample with blocking peptide on the right.
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