Mouse Monoclonal Antibody to JAK2
货号：
P20502
别名：
JAK2; Tyrosine-protein kinase JAK2; Janus kinase 2; JAK-2
应用：
IHC
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
O60674
规格：
目录价
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Description |
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Phosphorylated STATs then form homodimer or heterodimers and translocate to the nucleus to activate gene transcription. For example, cell stimulation with erythropoietin (EPO) during erythropoiesis leads to JAK2 autophosphorylation, activation, and its association with erythropoietin receptor (EPOR) that becomes phosphorylated in its cytoplasmic domain. Then, STAT5 (STAT5A or STAT5B) is recruited, phosphorylated and activated by JAK2. |
Specification |
|
|---|---|
| Aliases | JAK2; Tyrosine-protein kinase JAK2; Janus kinase 2; JAK-2 |
| Entrez GeneID | 3717 |
| Swissprot | O60674 |
| clone | 10A4 |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide conjugated to KLH. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol. |
Application |
|
|---|---|
| IHC | 1/50-1/100 |
Product Image
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Immunohistochemistry analysis of paraffin-embedded Human Lung Carcinoma Tissue using JAK2 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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Immunohistochemical analysis of paraffin-embedded Human tonsils using JAK2 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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