Mouse Monoclonal Antibody to XRCC4
货号：
P20664
别名：
X ray repair cross complementing protein 4; DNA repair protein XRCC4; DNA double strand break repair
应用：
WB,IP,IHC,IF
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
Q13426
规格：
目录价
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Description |
|---|
Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends. |
Specification |
|
|---|---|
| Aliases | X ray repair cross complementing protein 4; DNA repair protein XRCC4; DNA double strand break repair |
| Entrez GeneID | 7518 |
| Swissprot | Q13426 |
| clone | 7C5 |
| WB Predicted band size | Calculated MW: 38 kDa; Observed MW: 38-45 kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic Peptide of XRCC4 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IP | 1/10-1/20 |
| IHC | 1/50-1/100 |
| IF | 1/50-1/200 |
Product Image
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Western blot analysis of XRCC4 in XRCC4 in T47D, 3T3, COS7, C6 and Hela lysates using XRCC4 antibody
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Immunoprecipitation analysis of XRCC4 in Hela lysates using XRCC4 antibody.
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Immunohistochemistry analysis of paraffin-embedded XRCC4 in Human lung cancer using XRCC4 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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