Mouse Monoclonal Antibody to alpha Smooth Muscle Actin
货号：
P20674
别名：
ACTA2; ACTSA; ACTVS; GIG46; Actin; aortic smooth muscle; Alpha-actin-2; Cell growth-inhibiting gene 46 protein; α-SMA
应用：
WB,IHC,IF
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P62736
规格：
目录价
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Description |
|---|
Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Defects in ACTA2 are the cause of aortic aneurysm familial thoracic type 6 (AAT6) [MIM:611788]. They are primarily associated with a characteristic histologic appearance known as 'medial necrosis' or 'Erdheim cystic medial necrosis' in which there is degeneration and fragmentation of elastic fibers, loss of smooth muscle cells, and an accumulation of basophilic ground substance. |
Specification |
|
|---|---|
| Aliases | ACTA2; ACTSA; ACTVS; GIG46; Actin; aortic smooth muscle; Alpha-actin-2; Cell growth-inhibiting gene 46 protein; α-SMA |
| Entrez GeneID | 59 |
| Swissprot | P62736 |
| clone | 1D10 |
| WB Predicted band size | Calculated MW: 42 kDa; Observed MW: 42 kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic Peptide of α-SMA |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
| IF | 1/50-1/200 |
Product Image
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Western blot analysis of alpha Smooth Muscle Actin in αSmooth Muscle Actin in rat Brain, MCF-7, C6 and 3T3 lysates using alpha Smooth Muscle Actin antibody
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Western blot analysis of alpha Smooth Muscle Actin in Hela, A549, HL6, U2OS, C6 lysates using alpha Smooth Muscle Actin antibody
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Immunohistochemistry analysis of paraffin-embedded mouse Cecal Tissue using alpha Smooth Muscle Actin antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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