Mouse Monoclonal Antibody to p53
货号：
P20678
别名：
TP53; P53; Cellular tumor antigen p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53
应用：
WB,IHC,IF
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P04637
规格：
目录价
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Description |
|---|
Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains. |
Specification |
|
|---|---|
| Aliases | TP53; P53; Cellular tumor antigen p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53 |
| Entrez GeneID | 7157 |
| Swissprot | P04637 |
| clone | 2G5 |
| WB Predicted band size | Calculated MW: 44 kDa; Observed MW: 53 kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthetic Peptide of p53 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
| IF | 1/50-1/200 |
Product Image
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Western blot analysis of p53 in T47D and COS7 lysates using p53 antibody
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Immunofluorescence analysis of p53 in Hela using p53 antibody (Left) and DAPI (Right).
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Immunohistochemistry analysis of paraffin-embedded Human colon cancer tissue using p53 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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