Mouse Monoclonal Antibody to GRP78 BiP
货号：
P20783
别名：
HSPA5; GRP78; 78 kDa glucose-regulated protein; GRP-78; Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78; Heat shock 70 kDa protein 5; Immunoglobulin heavy chain-binding protein; BiP
应用：
WB,IP,IF
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P11021
规格：
目录价
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Description |
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When Chinese hamster K12 cells are starved of glucose, the synthesis of several proteins, called glucose-regulated proteins (GRPs), is markedly increased. Hendershot et al. (1994) (PubMed 8020977) pointed out that one of these, GRP78 (HSPA5), also referred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER). |
Specification |
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|---|---|
| Aliases | HSPA5; GRP78; 78 kDa glucose-regulated protein; GRP-78; Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78; Heat shock 70 kDa protein 5; Immunoglobulin heavy chain-binding protein; BiP |
| Entrez GeneID | 3309 |
| Swissprot | P11021 |
| clone | 7H10 |
| WB Predicted band size | Calculated MW: 72 kDa; Observed MW: 78 kDa |
| Host/Isotype | Mouse IgG2b |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Purified recombinant human BiP/GRP78 protein expressed in E.coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IP | 1/10-1/20 |
| IF | 1/50-1/200 |
Product Image
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Western blot analysis of GRP78 BiP in 3T3, A549, C6 and Hela lysates using BiP/GRP78 antibody.
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Immunoprecipitation analysis of GRP78 BiP in Hela lysates using BiP/GRP78 antibody.Western blot analysis of BiP/GRP78 using BiP/GRP78 antibody.
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Immunofluorescence analysis of GRP78 BiP in Hela using BiP/GRP78 antibody.
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