Mouse Monoclonal Antibody to Cleaved-Caspase 8
货号：
P20791
别名：
CASP8; MCH5; Caspase-8; CASP-8; Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; FADD-homologous ICE/ced-3-like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; MORT1-associated ced-3 homolog; MACH
应用：
WB,IHC,IF
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
Q14790
规格：
目录价
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Description |
|---|
This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. |
Specification |
|
|---|---|
| Aliases | CASP8; MCH5; Caspase-8; CASP-8; Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; FADD-homologous ICE/ced-3-like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; MORT1-associated ced-3 homolog; MACH |
| Entrez GeneID | 841 |
| Swissprot | Q14790 |
| WB Predicted band size | Calculated MW: 55 kDa; Observed MW: 43,57 kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant Protein of Caspase-8 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
| IF | 1/50-1/200 |
Product Image
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Western blot analysis of Caspase8 in K562, 3T3, MCF-7 and Jurkat lysates using Caspase8 antibody.
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Western blot analysis of Caspase 8 (2G12) in THP-1, rat Brain, Hela lysates using Caspase8 antibody.
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Western blot analysis of Caspase 8 (2G12) in Jurkat, MOLT4 lysates using Caspase 8 (2G12) antibody
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Immunocytochemistry analysis of Caspase8 (green) in Hela using Caspase8 antibody,and DAPI(blue).
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Immunohistochemistry analysis of paraffin-embedded mouse Spleen Tissue using Caspase8 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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