Rabbit Monoclonal Antibody to PKR
货号:
P20875
别名:
EIF2AK2; PKR; PRKR; Interferon-induced; double-stranded RNA-activated protein kinase; Eukaryotic translation initiation factor 2-alpha kinase 2; eIF-2A protein kinase 2; Interferon-inducible RNA-dependent protein kinase; P1/eIF-2A protein k
应用:
WB,IP,IHC,IF
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
P19525
规格:
目录价
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Description |
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PKR a protein kinase of the PEK family. Upon binding double-stranded RNA, it becomes autophosphorylated and activated. Phosphorylates and inhibits the alpha subunit of eIF2 alpha, which leads to an inhibition of the initiation of protein synthesis. |
Specification |
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Aliases | EIF2AK2; PKR; PRKR; Interferon-induced; double-stranded RNA-activated protein kinase; Eukaryotic translation initiation factor 2-alpha kinase 2; eIF-2A protein kinase 2; Interferon-inducible RNA-dependent protein kinase; P1/eIF-2A protein k |
Entrez GeneID | 5610 |
Swissprot | P19525 |
WB Predicted band size | Calculated MW: 62 kDa; Observed MW: 74 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | A synthetic peptide of human PKR |
Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
Application |
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WB | 1/500-1/1000 |
IP | 1/10-1/20 |
IHC | 1/50-1/100 |
IF | 1/50-1/200 |
Product Image
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Western blot analysis of PKR in K562, Hela lysates using PKR antibody.
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Immunocytochemistry analysis of PKR(green) in Hela using PKR antibody,and DAPI(blue)
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Immunohistochemistry analysis of paraffin-embedded Human Cholangiocarcinoma using PKR antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.