Rabbit Monoclonal Antibody to ATM
货号：
P20897
别名：
ATM; Serine-protein kinase ATM; Ataxia telangiectasia mutated; A-T mutated
应用：
WB,IF
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q13315
规格：
目录价
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Description |
|---|
The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. |
Specification |
|
|---|---|
| Aliases | ATM; Serine-protein kinase ATM; Ataxia telangiectasia mutated; A-T mutated |
| Entrez GeneID | 472 |
| Swissprot | Q13315 |
| WB Predicted band size | Calculated MW: 351 kDa; Observed MW: 351 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | A synthetic peptide of human ATM |
| Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IF | 1/50-1/200 |
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