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Mouse Monoclonal Antibody to mTOR
货号: 30910
别名: FRAP; FRAP1; FRAP2; RAFT1; RAPT1
应用: IHC
反应种属: Human,Mouse,Rat,Rabbit
抗体类型: Primary antibody
Swissprot: P42345
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Description

The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene.

References

1.Br J Cancer. 2015 Mar 17;112(6):1042-51.
2.Clin Cancer Res. 2014 Nov 1;20(21):5412-22.

Specification

Aliases FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Entrez GeneID 2475
Swissprot P42345
clone 8H5A5
WB Predicted band size 289kDa
Host/Isotype Mouse IgG2a
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat,Rabbit
Immunogen Purified recombinant fragment of human mTOR (AA: 2311-2529) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

IHC 1/200 - 1/1000
ELISA 1/10000
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