Rabbit Monoclonal Antibody to Argonaute 2
货号：
P21072
别名：
Ago 2; Argonaute 2; dAgo2; eIF2C 2; hAgo2; PPD
应用：
WB,IP,IF
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q9UKV8
规格：
目录价
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Description |
|---|
Required for RNA-mediated gene silencing (RNAi) by the RNA-induced silencing complex (RISC). Can also upregulate the translation of specific mRNAs under certain growth conditions. Binds to the AU element of the 3'-UTR of the TNF (TNF-alpha) mRNA and upregulates translation under conditions of serum starvation. Also required for transcriptional gene silencing (TGS), in which short RNAs known as antigene RNAs or agRNAs direct the transcriptional repression of complementary promoter regions. |
Specification |
|
|---|---|
| Aliases | Ago 2; Argonaute 2; dAgo2; eIF2C 2; hAgo2; PPD |
| Entrez GeneID | 27161 |
| Swissprot | Q9UKV8 |
| WB Predicted band size | Calculated MW: 97 kDa; Observed MW: 97 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | A synthetic peptide of human Argonaute-2 |
| Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IP | 1/10-1/20 |
| IF | 1/50-1/200 |
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