Rabbit Monoclonal Antibody to BRAT1
货号:
P21136
别名:
BRCA1-associated ATM activator 1; BRCA1-associated protein required for ATM activation protein 1
应用:
WB,IP
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
Q6PJG6
规格:
目录价
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Description |
|---|
Involved in DNA damage response; activates kinases ATM, SMC1A and PRKDC by modulating their phosphorylation status following ionizing radiation (IR) stress (PubMed:16452482, PubMed:22977523). Plays a role in regulating mitochondrial function and cell proliferation (PubMed:25070371). Required for protein stability of MTOR and MTOR-related proteins, and cell cycle progress by growth factors (PubMed:25657994). |
Specification |
|
|---|---|
| Aliases | BRCA1-associated ATM activator 1; BRCA1-associated protein required for ATM activation protein 1 |
| Entrez GeneID | 221927 |
| Swissprot | Q6PJG6 |
| WB Predicted band size | Calculated MW: 88 kDa; Observed MW: 88 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Recombinant protein of human BRAT1 |
| Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IP | 1/10-1/20 |


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