Rabbit Monoclonal Antibody to Caspase 11
货号：
P21162
别名：
Caspl; ich-3; CASP-4; Casp11; CASP-11
应用：
WB,IP
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P70343
规格：
目录价
在线咨询
Description |
|---|
Proinflammatory caspase. Essential effector of NLRP3 inflammasome-dependent CASP1 activation and IL1B and IL18 secretion in response to non-canonical activators, such as UVB radiation, cholera enterotoxin subunit B and cytosolic LPS, as well as infection with Gram-negative bacteria. Independently of NLRP3 inflammasome and CASP1, promotes pyroptosis, through GSDMD cleavage and activation, and IL1A, IL18 and HMGB1 release in response to non-canonical inflammasome activators. |
Specification |
|
|---|---|
| Aliases | Caspl; ich-3; CASP-4; Casp11; CASP-11 |
| Entrez GeneID | 12363 |
| Swissprot | P70343 |
| WB Predicted band size | Calculated MW: 43 kDa; Observed MW: 43,38,25 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein of mouse Caspase-11 |
| Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IP | 1/10-1/20 |
鄂公网安备42018502007531号
