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Rabbit Monoclonal Antibody to CIRBP
货号: P21229
别名: CIRP
应用: WB,IP,IHC
反应种属: Human
抗体类型: Primary antibody
Swissprot: Q14011
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Description

Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor . Promotes assembly of stress granules (SGs), when overexpressed.

Specification

Aliases CIRP
Entrez GeneID 1153
Swissprot Q14011
WB Predicted band size Calculated MW: 19 kDa; Observed MW: 19 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Recombinant protein of human CIRBP
Formulation Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Application

WB 1/500-1/1000
IP 1/10-1/20
IHC 1/50-1/100
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