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Mouse Monoclonal Antibody to TSHB
货号: 30942
别名: TSH-B; TSH-BETA
应用: IHC,FCM
反应种属: Human
抗体类型: Primary antibody
Swissprot: P01222
规格:
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Description

The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by this gene is the beta subunit of thyroid stimulating hormone. Mutations in this gene are associated with congenital central and secondary hypothyroidism and Hashimoto's thyroiditis. Alternative splicing of this gene results in multiple transcript variants.

References

1.Mol Biol Rep. 2012 Dec;39(12):10019-30.
2.Thyroid. 2010 Jun;20(6):639-45.

Specification

Aliases TSH-B; TSH-BETA
Entrez GeneID 7252
Swissprot P01222
clone 1D12G1
WB Predicted band size 15.6kDa
Host/Isotype Mouse IgG2b
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human TSHB (AA: 20-139) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

IHC 1/200 - 1/1000
FCM 1/200 - 1/400
ELISA 1/10000
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