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Rabbit Monoclonal Antibody to FADD
货号: P21376
别名: Mort1/FADD
应用: WB,IHC
反应种属: Human,Mouse
抗体类型: Primary antibody
Swissprot: Q61160
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Description

Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis . Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling .

Specification

Aliases Mort1/FADD
Entrez GeneID 14082
Swissprot Q61160
WB Predicted band size Calculated MW: 23 kDa; Observed MW: 28 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse
Immunogen A synthetic peptide of mouse FADD
Formulation Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Application

WB 1/500-1/1000
IHC 1/50-1/100
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