Rabbit Monoclonal Antibody to FADD
货号:
P21376
别名:
Mort1/FADD
应用:
WB,IHC
反应种属:
Human,Mouse
抗体类型:
Primary antibody
Swissprot:
Q61160
规格:
目录价
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Description |
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Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis . Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling . |
Specification |
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Aliases | Mort1/FADD |
Entrez GeneID | 14082 |
Swissprot | Q61160 |
WB Predicted band size | Calculated MW: 23 kDa; Observed MW: 28 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse |
Immunogen | A synthetic peptide of mouse FADD |
Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
Application |
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WB | 1/500-1/1000 |
IHC | 1/50-1/100 |
Product Image
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Western blot analysis of FADD in Raw264.7 lysates using FADD antibody.
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Western blot analysis of FADD in SH-SY5Y lysates using FADD antibody
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Immunohistochemistry analysis of paraffin-embedded mouse liver using FADD antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.