Rabbit Monoclonal Antibody to hnRNP K
货号：
P21515
别名：
HNRNPK; HNRPK; Heterogeneous nuclear ribonucleoprotein K; hnRNP K; Transformation up-regulated nuclear protein; TUNP
应用：
WB,IP,IHC,IF
反应种属：
Human,Mouse,Rat,Hamster
抗体类型：
Primary antibody
Swissprot：
P61978
规格：
目录价
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Description |
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Facilitate pre-mRNA processing and transport of mRNA from the nucleus to cytoplasm. hnRNP K contains three unique structural motifs termed KH domains that bind poly(C) DNA and RNA sequences. Intricate architecture enables hnRNP K to facilitate mRNA biosynthesis, transcriptional regulation, and signal transduction. Research studies have shown that cytoplasmic hnRNP K expression is increased in oral squamous cell carcinoma and pancreatic cancer, and may be a potential prognostic factor. |
Specification |
|
|---|---|
| Aliases | HNRNPK; HNRPK; Heterogeneous nuclear ribonucleoprotein K; hnRNP K; Transformation up-regulated nuclear protein; TUNP |
| Entrez GeneID | 3190 |
| Swissprot | P61978 |
| WB Predicted band size | Calculated MW: 51 kDa; Observed MW: 58 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat,Hamster |
| Immunogen | A synthetic peptide of human hnRNP K |
| Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IP | 1/10-1/20 |
| IHC | 1/50-1/100 |
| IF | 1/50-1/200 |
Product Image
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Western blot analysis of hnRNP K in 3T3, MEF lysates using hnRNP K antibody.
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Western blot analysis of hnRNP K in C6, CHO-K1, Hela lysates using hnRNP K antibody.
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Immunocytochemistry analysis of hnRNP K (green) in MCF-7 using hnRNP K antibody,and DAPI(blue).
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Immunohistochemistry analysis of paraffin-embedded Human lung cancer using hnRNP K antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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