Rabbit Monoclonal Antibody to KMT6
货号:
P21605
别名:
WVS; ENX1; KMT6; WVS2; ENX-1; EZH2b; KMT6A; EZH2
应用:
WB,IF
反应种属:
Human,Mouse,Rat
抗体类型:
Primary antibody
Swissprot:
Q15910
规格:
目录价
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Description |
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Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Compared to EZH2-containing complexes, it is more abundant in embryonic stem cells and plays a major role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation. |
Specification |
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Aliases | WVS; ENX1; KMT6; WVS2; ENX-1; EZH2b; KMT6A; EZH2 |
Entrez GeneID | 2146 |
Swissprot | Q15910 |
WB Predicted band size | Calculated MW: 85 kDa; Observed MW: 98 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat |
Immunogen | A synthetic peptide of human KMT6/EZH2 |
Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
Application |
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WB | 1/500-1/1000 |
IF | 1/50-1/200 |