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Rabbit Monoclonal Antibody to MAGEA3
货号: P21636
别名: HIP8; HYPD; CT1.3; MAGE3; MAGEA6
应用: WB
反应种属: Human
抗体类型: Primary antibody
Swissprot: P43357
规格:
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Description

Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May play a role in embryonal development and tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.

Specification

Aliases HIP8; HYPD; CT1.3; MAGE3; MAGEA6
Entrez GeneID 4102
Swissprot P43357
WB Predicted band size Calculated MW: 35 kDa; Observed MW: 45 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Recombinant protein of human MAGEA3
Formulation Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Application

WB 1/500-1/1000
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