Rabbit Monoclonal Antibody to NCAPH2
货号:
P21714
别名:
CAPH2
应用:
WB,IP,IHC,IF
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
Q6IBW4
规格:
目录价
在线咨询
Description |
---|
Regulatory subunit of the condensin-2 complex, a complex that seems to provide chromosomes with an additional level of organization and rigidity and in establishing mitotic chromosome architecture (PubMed:14532007). May promote the resolution of double-strand DNA catenanes (intertwines) between sister chromatids. Condensin-mediated compaction likely increases tension in catenated sister chromatids, providing directionality for type II topoisomerase-mediated strand exchanges toward chromatid decatenation. Required for decatenation of chromatin bridges at anaphase. Early in neurogenesis, may play an essential role to ensure accurate mitotic chromosome condensation in neuron stem cells, ultimately affecting neuron pool and cortex size . Seems to have lineage-specific role in T-cell development (PubMed:14532007). |
Specification |
|
---|---|
Aliases | CAPH2 |
Entrez GeneID | 29781 |
Swissprot | Q6IBW4 |
WB Predicted band size | Calculated MW: 68 kDa; Observed MW: 68 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | A synthetic peptide of human NCAPH2 |
Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
Application |
|
---|---|
WB | 1/500-1/1000 |
IP | 1/10-1/20 |
IHC | 1/50-1/100 |
IF | 1/50-1/200 |