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Rabbit Monoclonal Antibody to Nicastrin
货号: P21751
别名: APH2; Ncstn; NCT; Nicastrin
应用: WB,IP
反应种属: Human,Mouse,Rat
抗体类型: Primary antibody
Swissprot: Q92542
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Description

Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex.

Specification

Aliases APH2; Ncstn; NCT; Nicastrin
Entrez GeneID 23385
Swissprot Q92542
WB Predicted band size Calculated MW: 78 kDa; Observed MW: 110-120 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen A synthetic peptide of human Nicastrin
Formulation Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Application

WB 1/500-1/1000
IP 1/10-1/20
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