Rabbit Monoclonal Antibody to NOLC1
货号：
P21758
别名：
P130; NOPP130; NOPP140; NS5ATP13
应用：
WB,IHC,IF
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q14978
规格：
目录价
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Description |
|---|
Nucleolar protein that acts as a regulator of RNA polymerase I by connecting RNA polymerase I with enzymes responsible for ribosomal processing and modification (PubMed:10567578, PubMed:26399832). Required for neural crest specification: following monoubiquitination by the BCR(KBTBD8) complex, associates with TCOF1 and acts as a platform to connect RNA polymerase I with enzymes responsible for ribosomal processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification (PubMed:26399832). Involved in nucleologenesis, possibly by playing a role in the maintenance of the fundamental structure of the fibrillar center and dense fibrillar component in the nucleolus (PubMed:9016786). It has intrinsic GTPase and ATPase activities (PubMed:9016786). |
Specification |
|
|---|---|
| Aliases | P130; NOPP130; NOPP140; NS5ATP13 |
| Entrez GeneID | 9221 |
| Swissprot | Q14978 |
| WB Predicted band size | Calculated MW: 74 kDa; Observed MW: 110 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | A synthetic peptide of human NOLC1 |
| Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
| IF | 1/50-1/200 |
Product Image
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Western blot analysis of NOLC1 in Jurkat lysates using NOLC1 antibody.
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Immunocytochemistry analysis of NOLC1 (green) in Hela using NOLC1 antibody,and DAPI(blue)
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Immunohistochemistry analysis of paraffin-embedded Human breast cancer using NOLC1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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