Rabbit Monoclonal Antibody to Nesprin3
货号:
P21740
别名:
KASH3; NET53; Nesp3; C14orf49; C14orf139; LINC00341; NCRNA00341
应用:
WB
反应种属:
Human
抗体类型:
Primary antibody
Swissprot:
Q6ZMZ3
规格:
目录价
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Description |
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As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Plays a role in the regulation of aortic epithelial cell morphology, and is required for flow-induced centrosome polarization and directional migration in aortic endothelial cells. |
Specification |
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Aliases | KASH3; NET53; Nesp3; C14orf49; C14orf139; LINC00341; NCRNA00341 |
Entrez GeneID | 161176 |
Swissprot | Q6ZMZ3 |
WB Predicted band size | Calculated MW: 112 kDa; Observed MW: 112 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Recombinant protein of human Nesprin3 |
Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
Application |
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WB | 1/500-1/1000 |