Rabbit Monoclonal Antibody to NUMB
货号：
P21774
别名：
NUMB; Protein numb homolog; h-Numb; Protein S171
应用：
WB,IP,IHC
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P49757
规格：
目录价
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Description |
|---|
Numb acts as a negative regulator of Notch signaling by promoting ubiquitination and degradation of Notch. The protein is asymmetrically segregated into one daughter cell during cell division, producing two daughter cells with different responses to Notch signaling and different cell fates. The localization of Numb can also be regulated by G-protein coupled receptor (GPCR) and PKC signaling. |
Specification |
|
|---|---|
| Aliases | NUMB; Protein numb homolog; h-Numb; Protein S171 |
| Entrez GeneID | 8650 |
| Swissprot | P49757 |
| WB Predicted band size | Calculated MW: 71 kDa; Observed MW: 71 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein of human NUMB |
| Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IP | 1/10-1/20 |
| IHC | 1/50-1/100 |
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