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Rabbit Monoclonal Antibody to PAIP1
货号: P21804
别名: poly(A) binding protein interacting protein 1
应用: WB,IP,IHC,IF
反应种属: Human,Mouse,Rat
抗体类型: Primary antibody
Swissprot: Q9H074
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Description

Acts as a coactivator in the regulation of translation initiation of poly(A)-containing mRNAs. Its stimulatory activity on translation is mediated via its action on PABPC1. Competes with PAIP2 for binding to PABPC1. Its association with EIF4A and PABPC1 may potentiate contacts between mRNA termini. May also be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.

Specification

Aliases poly(A) binding protein interacting protein 1
Entrez GeneID 10605
Swissprot Q9H074
WB Predicted band size Calculated MW: 54 kDa; Observed MW: 54 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen A synthetic peptide of human PAIP1
Formulation Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Application

WB 1/500-1/1000
IP 1/10-1/20
IHC 1/50-1/100
IF 1/50-1/200
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