Rabbit Monoclonal Antibody to PP2A alpha/beta
货号：
P21868
别名：
PPP2CA; Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A-alpha; Replication protein C; RP-C
应用：
WB,IP,IHC,IF
反应种属：
Human,Mouse,Rat,Hamster
抗体类型：
Primary antibody
Swissprot：
P67775
规格：
目录价
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Description |
|---|
PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGOL2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'. |
Specification |
|
|---|---|
| Aliases | PPP2CA; Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A-alpha; Replication protein C; RP-C |
| Entrez GeneID | 5515 |
| Swissprot | P67775 |
| WB Predicted band size | Calculated MW: 36 kDa; Observed MW: 36 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat,Hamster |
| Immunogen | A synthetic peptide of human PP2A alpha |
| Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IP | 1/10-1/20 |
| IHC | 1/50-1/100 |
| IF | 1/50-1/200 |
Product Image
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Western blot analysis of PP2A alpha/beta in C2C12, 3T3, mouse brain lysates using PP2A alpha/beta antibody.
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Western blot analysis of PP2A alpha/beta in rat Brain, C6, CHO-K1, Hela lysates using PP2A alpha/beta antibody.
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Immunocytochemistry analysis of PP2A alpha/beta (green) in hela using PP2A alpha/beta antibody,and DAPI(blue).
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Immunohistochemistry analysis of paraffin-embedded Human lung cancer using PP2A alpha/beta antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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