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Rabbit Monoclonal Antibody to POT1
货号: P21867
别名: POT1; Protection of telomeres protein 1; hPot1; POT1-like telomere end-binding protein
应用: WB
反应种属: Human,Mouse,Rat
抗体类型: Primary antibody
Swissprot: Q9NUX5
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Description

This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.

Specification

Aliases POT1; Protection of telomeres protein 1; hPot1; POT1-like telomere end-binding protein
Entrez GeneID 25913
Swissprot Q9NUX5
WB Predicted band size Calculated MW: 71 kDa; Observed MW: 71 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen A synthetic peptide of human POT1
Formulation Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Application

WB 1/500-1/1000
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