Rabbit Monoclonal Antibody to POT1
货号:
P21867
别名:
POT1; Protection of telomeres protein 1; hPot1; POT1-like telomere end-binding protein
应用:
WB
反应种属:
Human,Mouse,Rat
抗体类型:
Primary antibody
Swissprot:
Q9NUX5
规格:
目录价
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Description |
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This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described. |
Specification |
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Aliases | POT1; Protection of telomeres protein 1; hPot1; POT1-like telomere end-binding protein |
Entrez GeneID | 25913 |
Swissprot | Q9NUX5 |
WB Predicted band size | Calculated MW: 71 kDa; Observed MW: 71 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat |
Immunogen | A synthetic peptide of human POT1 |
Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
Application |
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WB | 1/500-1/1000 |