Rabbit Monoclonal Antibody to SMAC
货号:
P22019
别名:
SMAC; DFNA64; DIABLO; SMAC3
应用:
WB,IP,IHC,IF
反应种属:
Human,Mouse,Rat
抗体类型:
Primary antibody
Swissprot:
Q9NR28
规格:
目录价
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Description |
|---|
Smac/Diablo is a 21 kDa mammalian mitochondrial protein that functions as a regulatory component during apoptosis. Upon mitochondrial stress, Smac/Diablo is released from mitochondria and competes with caspases for binding of IAPs (inhibitor of apoptosis proteins). The interaction of Smac/Diablo with IAPs relieves the inhibitory effect of the IAPs on caspases. |
Specification |
|
|---|---|
| Aliases | SMAC; DFNA64; DIABLO; SMAC3 |
| Entrez GeneID | 56616 |
| Swissprot | Q9NR28 |
| WB Predicted band size | Calculated MW: 27 kDa; Observed MW: 21 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | A synthetic peptide of human Smac/Diablo |
| Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IP | 1/10-1/20 |
| IHC | 1/50-1/100 |
| IF | 1/50-1/200 |
Product Image
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Western blot analysis of Smac/Diablo in mouse heart, rat skin lysates using SMAC antibody.

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Western blot analysis of Smac/Diablo in K562, Hela lysates using Smac/Diablo antibody.

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Immunocytochemistry analysis of Smac/Diablo(green) in Hela using Smac/Diablo antibody,and DAPI(blue)

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Immunohistochemistry analysis of paraffin-embedded Human tonsil using Smac/Diablo antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.





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