Rabbit Monoclonal Antibody to SSX2IP
货号:
P22044
别名:
ADIP; hMsd1
应用:
WB,IHC,IF
反应种属:
Human,Rat
抗体类型:
Primary antibody
Swissprot:
Q9Y2D8
规格:
目录价
在线咨询
Description |
---|
Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). May connect the nectin-afadin and E-cadherin-catenin system through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and alpha-actinin . Involved in cell movement: localizes at the leading edge of moving cells in response to PDGF and is required for the formation of the leading edge and the promotion of cell movement, possibly via activation of Rac signaling . Acts as a centrosome maturation factor, probably by maintaining the integrity of the pericentriolar material and proper microtubule nucleation at mitotic spindle poles. The function seems to implicate at least in part WRAP73; the SSX2IP:WRAP73 complex is proposed to act as regulator of spindle anchoring at the mitotic centrosome (PubMed:23816619, PubMed:26545777). Involved in ciliogenesis (PubMed:24356449). It is required for targeted recruitment of the BBSome, CEP290, RAB8, and SSTR3 to the cilia (PubMed:24356449). |
Specification |
|
---|---|
Aliases | ADIP; hMsd1 |
Entrez GeneID | 117178 |
Swissprot | Q9Y2D8 |
WB Predicted band size | Calculated MW: 71 kDa; Observed MW: 71 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Rat |
Immunogen | A synthetic peptide of human SSX2IP |
Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
Application |
|
---|---|
WB | 1/500-1/1000 |
IHC | 1/50-1/100 |
IF | 1/50-1/200 |
Product Image
-
Western blot analysis of SSX2IP in rat kidney lysates using SSX2IP antibody.
-
Western blot analysis of SSX2IP in Jurkat, Hela lysates using SSX2IP antibody
-
Immunocytochemistry analysis of SSX2IP (green) in K562 using SSX2IP antibody,and DAPI(blue).
-
Immunohistochemistry analysis of paraffin-embedded Human Brain using SSX2IP antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.