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Mouse Monoclonal Antibody to SYN1
货号: 31015
别名: SYNI; SYN1a; SYN1b
应用: WB,IHC,IF,FCM
反应种属: Human,Mouse,Monkey,Rat
抗体类型: Primary antibody
Swissprot: P17600
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Description

This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

References

1.Synapse. 2012 Nov;66(11):979-83.
2.J Neurosci Res. 2009 Aug 1;87(10):2255-63.

Specification

Aliases SYNI; SYN1a; SYN1b
Entrez GeneID 6853
Swissprot P17600
clone 7H10G6
WB Predicted band size 74.1kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Monkey,Rat
Immunogen Purified recombinant fragment of human SYN1 (AA: 362-511) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

WB 1/500 - 1/2000
IHC 1/200 - 1/1000
IF 1/200 - 1/1000
FCM 1/200 - 1/400
ELISA 1/10000
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