Rabbit Monoclonal Antibody to U1C
货号：
P22141
别名：
U1 small nuclear ribonucleoprotein C; U1 snRNP C; U1-C
应用：
WB,IP,IHC,IF
反应种属：
Human,Rat
抗体类型：
Primary antibody
Swissprot：
P09234
规格：
目录价
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Description |
|---|
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. |
Specification |
|
|---|---|
| Aliases | U1 small nuclear ribonucleoprotein C; U1 snRNP C; U1-C |
| Entrez GeneID | 6631 |
| Swissprot | P09234 |
| WB Predicted band size | Calculated MW: 17 kDa; Observed MW: 21 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Rat |
| Immunogen | A synthetic peptide of human U1-C |
| Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
Application |
|
|---|---|
| WB | 1/500-1/1000 |
| IP | 1/10-1/20 |
| IHC | 1/50-1/100 |
| IF | 1/50-1/200 |
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